Neuropathic Pain

Neuropathic pain is a complex and chronic pain state resulting from nerve damage (neuropathy) and unlike a normal response of acute pain associated with an injury, neuropathic pain is an abnormal response that is chronic and debilitating.


Neuropathic pain is usually perceived as a steady burning and/or "pins and needles" and/or "electric shock" sensations. One example of neuropathic pain is called phantom limb syndrome. This occurs when an arm or a leg has been removed because of illness or injury, but the brain still gets pain messages from the nerves that originally carried impulses from the missing limb. 

Apart from phantom limb syndrome, the common causes of neuropathy are diabetes, cancer, herpes zoster infection, HIV-AIDS, toxins, alcoholism, chronic trauma (such as repetitive motion disorders) or acute trauma (including surgery). In many cases no apparent causes can be found, in this case the neuropathy is "idiopathic" meaning no cause is found.


Research has shown that neuropathy and the associated neupathic pain states can be treated successfully with systemically injected Neublastin (also known as artemin or enovin). Neublastin also achieves partial to complete reversal of associated morphological and neurochemical changes. (Visit Nature Medicine website to read the article "Multiple actions of systemic artemin in experimental neuropathy"). With a market prevalence of 37.6 million patients (Source: Business Insights) Neublastin has the potential of becoming a blockbuster product. 
 

 
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